I've been using DbVisualizer for years and think it is great. It is Java-based, so using it on Windows, Linux, and Mac, at home or at work, is easy. Regardless of what (usually sub-par) database client each workplace I find myself in tries to steer me to, I usually end up using my copy of DbVisualizer.
The licensing is reasonably-priced and updates are frequent. I've used it with Oracle, MySQL, PostgreSQL, Sybase, DB2, etc. The one thing I would like to see is support for exporting my database connections info. But that is a small issue.
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